Phone: +33 (0)1 34 86 77 01 | email :


Innovative range of integrated systems for pathology



SpotBrowser® 4

Spot Browser® 4 runs on microscopes and interfaces with most scanners on the market.

Spot identification is undoubtedly the most time-consuming and difficult stage in preparing tissue array spots for analysis. Identification includes detecting spots on the slide scan, then associating each of these spots with their respective position in the initial plan of your Arrays tissue, to create the essential traceability link between spot and patient data.

Spot Browser® 4 includes a de-Arraying tool for data detection and association. Simply import your tissue array map file, and Spot Browser® 4 takes care of the rest. Interactions and corrections are always possible in cases where the Tissue Array is truly in poor condition on the blade (severe deformations).

Annotation on tissue array spots

In many cases, spots are “scored” visually, because the pathologist’s expert eye cannot so easily be replaced by software, however powerful.

To meet this need, Spot Browser® 4 allows users to create their own data fields in various formats (free, numeric, drop-down list…) to enter their annotations. The user can quickly navigate from one spot to another and enter annotations.

Input and imported data can be exported in Excel format for statistical processing.

Automatic analysis of tissue array spots

For analysis of large numbers of spots or for quantitative analysis, Spot Browser® 4 offers a comprehensive tool for automatic image analysis.

HSV color and morphometry are the characteristics used. Each of these features can be used alone or in combination, depending on the objects to be detected.

Users can easily create their own detection protocols, with one or more types of object to be detected, and with or without nesting, for example, to count labeled nuclei in a tumor zone. Cytoplasmic and membrane labelling can also be detected.

Detection and analysis protocols can be saved in internal libraries for future use.

The user can analyze spots one by one or in automatic batch mode, and analyses can combine human intervention (zone tracing, for example) with fully automatic modes.

Raw and interpreted results can be exported to Excel.


Ultra-fast freezing system for tissue samples without liquid nitrogen

SnapFrost® guarantees ultra-fast, reproducible freezing of your samples.

The reference technique using Iso pentane refrigerated down to -80°C, which unlike liquid nitrogen does not degas, enables rapid, reproducible temperature transmission to the sample.

Molecular content does not diffuse into the sample, cell membranes are preserved and tissue damage is avoided.

Ergonomic and flexible in use, SnapFrost® features two individually controllable freezing chambers to suit all freezing protocols and tissue types. The volume of the lower chamber containing Iso pentane can be modulated (from 5 to 680 ml) to suit all sample sizes.

Alternative solutions such as the Novec 7100 can also be used in the SnapFrost®, retaining the advantages of the appliance and guaranteeing high quality freezing.

Programmable, compact and autonomous, SnapFrost® can be moved to different freezing zones, guaranteeing flexibility, time savings, safety, quality and reproducibility in your freezing operations.