# Molecular Pathology

> MOLECULAR PATHOLOGY A simple, economical and proven solution Digital Pathology Integrated solutions for FISH Solutions for pathology Molecular Pathology Solutions for Cytogenetics Analysis of nanoparticles analyse cutting-edge technology Laser microdissection…

Source : https://www.excilone.com/en/molecular-pathology/
Mise à jour : 2025-11-12

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# MOLECULAR PATHOLOGY

A simple, economical and proven solution

[![](https://www.excilone.com/wp-content/uploads/2023/12/brightfield-150x150.webp)](https://www.excilone.com/en/digital-pathology/)

[Digital Pathology](https://www.excilone.com/en/digital-pathology/)

[![](https://www.excilone.com/wp-content/uploads/2023/12/Fish-coupe-150x150.webp)](https://www.excilone.com/en/integrated-solution-for-tissue-based-fish/)

[Integrated solutions for FISH](https://www.excilone.com/en/integrated-solution-for-tissue-based-fish/)

[![](https://www.excilone.com/wp-content/uploads/2024/01/Pathscan-touch-visuel-150x150.jpeg)](https://www.excilone.com/en/instrument-for-pathology/)

[Solutions for pathology](https://www.excilone.com/en/instrument-for-pathology/)

![](https://www.excilone.com/wp-content/uploads/2024/02/img-molecul-150x150.png)

Molecular Pathology

[![](https://www.excilone.com/wp-content/uploads/2024/02/img-cytogenetic-150x150.png)](https://www.excilone.com/en/solution-for-cytogenetics/)

[Solutions for Cytogenetics](https://www.excilone.com/en/solution-for-cytogenetics/)

[![](https://www.excilone.com/wp-content/uploads/2024/02/3d-render-background-with-cell-elements-medical-concept-with-abstract-molecules-150x150.jpg)](https://www.excilone.com/en/nano-particle-analysis/)

[Analysis of nanoparticles](https://www.excilone.com/en/nano-particle-analysis/)

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## cutting-edge technology

- Laser microdissection
- Automated tissue dissection

### ![](https://www.excilone.com/wp-content/uploads/2024/01/picto-site-excilone.webp) Accuva Cellect

#### **Accuva Cellect :** Laser Capture Microdissection (LCM) System ![](https://www.excilone.com/wp-content/uploads/2024/07/Accuva-Cellect-System-886x1024.jpg)

###### **Power and precision in one instrument**

- Soft IR laser, ideal for capturing single cells and small numbers of cells
- The UV laser offers superior speed and precision, optimal for dense tissue structures
- A simple and intuitive system enables rapid microdissection that improves downstream analysis

###### **Capture only the cells you need**

Isolate only the desired cells, and enrich for specific cell types to enable a more accurate genetic profile for early-stage analysis.

##### **Features and Benefits**

- **Dual-laser system**
  Enables a wide range of applications, from single-cell isolation to large-scale biopsy extractions, increasing flexibility and helping to ensure reliable cell capture on all sample types without contamination or morphological damage.
- **Intuitive software**
  Enables rapid isolation of specific cells in five simple steps and quality control with visual inspection, facilitating sample documentation and preservation.
- **Service and Support**
  Training and 48-hour response times to get you back to work.
- **Flexible Sample Preparation**
  Support for a wide range of slide types and sample preparation formats. If you have an existing workflow, we can work with it or help validate a workflow with you.
- **Compact Design**
  The footprint is approximately 32% smaller than other microscope and laser systems on the market, saving valuable bench space.

**More information about [laxcoinc](https://www.laxcoinc.com/lcm)**

![](https://www.excilone.com/wp-content/uploads/2025/05/MiniPunch-vu_3.png)

### ![](https://www.excilone.com/wp-content/uploads/2024/01/picto-site-excilone.webp) MiniPunch®

This innovative tool allows users to select an area of ​​interest from a digitized histological slide and automatically collect 200 µm diameter tissue samples from the corresponding paraffin block. This technology bridges the gap between histology and molecular analysis using artificial intelligence tools.

**•** Obtain molecular biology data from areas
as small as 200 µm in diameter

**•** Selection of areas of interest from digital slides

**•** Automated coring of areas of interest on paraffin blocks
(up to 16 blocks processed in a single run)

**•** Purification and extraction of DNA/RNA without deparaffinization

- # Benefits
- # Applications
- Consumables
- # Workflow
- # Technical specifications

**Compact and ergonomic system**

- Integrated touch screen.
- Keyboard and mouse stored in a drawer at the base.

**Advanced technology**

- Intuitive user interface: MiniPunch® software guides you step by step through the development of your project
- Automated tray with two removable supports (block and tube supports)
- Execution speed: approximately 40 seconds per sample

**Optimal traceability**

- Capture of the block ID and reading of the barcode to ensure traceability.
- Image capture at every key step of the process.
- Creation of an Excel tracking file.

**Extended compatibility**

ExciloneView® software allows you to view and select areas of interest on scanned slides. ExciloneView® is compatible with most slide scanners currently on the market.

Try the **free version of ExciloneView®** ([Digital pathology– Excilone](https://www.excilone.com/en/digital-pathology/)).

**Precision of tissue sampling**

- Ultra-precise sampling thanks to the automatic overlay of virtual slide annotations on the block image.
- Precise and reproducible definition of the core point.

**Large capacity**

- Up to 16 paraffin blocks/tray.
- A support for a 96-well plate or for a rack of microtube strips.
- Needle rack (96 needles/rack).

**Sample Preservation**

- RNase and DNase free single-use needles for molecular analyses.
- Small samples are taken to preserve paraffin blocks.

**The MiniPunch® is ideal for various applications in Oncology, Neurology, Immunology, Immuno-oncology, Infectiology and any other fields where molecular analysis (nucleic acid and protein) needs to be linked to an area of interest in FFPE tissue.**

Our R&D laboratory has verified the compatibility and feasibility of numerous analyses on these micro-samples, such as :

- Mutation research by qPCR, dPCR and NGS (with sequence capture probe)
- Gene expression level analysis by qRT-PCR, RT-dPCR and RNAseq

Excilone has also developed a proprietary technique for extracting nucleic acids without a deparaffinization step from FFPE micro-samples in order to carry out molecular analyses.

**Contact us** for more information.

| Needle plate* 200µm in diameter (96 units/plate) _*RNase & DNase free_ | **REF :** MiP-P96200 |
| --- | --- |

[![](https://www.excilone.com/wp-content/uploads/2025/05/worflow-Minipunch-EN-1-scaled.png)](https://www.excilone.com/wp-content/uploads/2025/05/worflow-Minipunch-EN-1-scaled.png)

_* Optional steps: only when the process is performed with scanned slides._

**CE marking :** Built to CE/CEM requirements and certified to these standards.

| **Components** | **Description** |
| --- | --- |
| **Dimensions** | Width : 560 mm Depth : 720 mm Height : 650 mm |
| **Weight** | Approximately 45 kg |
| **Alimentation** | 85/264 VAC, 0.8A à 230 VAC, 47/63 Hz |
| **Number of blocks** | Up to 16 per tray |
| **Needle** | 200 µm diameter – 96 units/rack |
| **Collector tube format** | 96-well microplate 0.1 or 0.2 ml strips or microtubes (0.5 ml coming soon) |
| **Work surface on the block** | 40 mm x 28 mm |
| **Max. paraffin thickness** | 10 mm |
| **Length of carrots** | Configurable |
| **Coring area** | Manual determination on the block image |
| **Speed** | Approximately 40 seconds per sample |

_Indicative but non-contractual specifications._

[Request more information](https://www.excilone.com/contact/)