PathScan® Combi

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Digital Pathology

FISH and Brightfield scanner

PathScan® Combi

Réf. : PathScanCombi

Product description

PathScan® Combi is a brightfield and fluorescence slide scanner for digital pathology and FISH analysis allowing fast, flexible and reliable navigation, acquisition, analysis, archiving and transfer of high quality digital images.

This scanner can acquire images with low-emission fluorochromes, as well (dual video cameras, monochrome, color). It allows the management of fluorescence preparations for as long as necessary in artificial or natural light without the risk of photobleaching and analyzes individual areas, nuclei and spots or whole preparations, in manual or semiautomatic mode.

Its automatic revolving turret offers a choice of 7 different objectives for a wide range of selectable magnifications with high focus precision and a perfect image quality. The digital microscope allows real-time browsing and workflow control from remote workstations.

PathScan® Combi can include as option dedicated analysis modules (membranes, nuclei) for tumor analysis with standardized and reproducible evaluation methods. The TMA module (SpotBrowser 4) is also fully integrated and permits the evaluation and scoring of several hundred samples on a single slide.

PathScan® Combi performs full-field image matching between brightfield and fluorescence to perform FISH analysis in the same tumor area of a pre-analyzed section.

PathScan® Combi is a valuable support for target therapy as well thanks to its dedicated analysis modules: Her-2 FISH, ALK FISH and translocations, FISH spot counting.

With its dedicated Web application, PathScan® Combi assures remote unlimited access to acquired images and password-protected access to individual files and working environments. PathScan® Combi has a dedicated joystick designed for both right and left hand use. Zoom, one touch image reduction and enlargement, X, Y navigation, magnification and navigation speed can be fully controlled through the Joystick

Hardware specifications

2x, 4x, 10x, 20x, 40x, 60x Oil immersion

Scanning speed
Brightfield – Few minutes to perform a complete slide scan at 20x
Fluorescence – 25 seconds per z-stack field for Her-2 FISH at 60x Oil immersion

8 slides

Software specifications

  • Complete database management
  • Automated host interface
  • Automated scanning procedure
  • Digital microscope (slide viewing in live mode)
  • Remote digital microscope
  • Z-stack acquisition for FISH analysis
  • Quantitative image analysis for digital pathology      and FISH
  • Web interface for remote reviewing of digitized      slides and sharing (e.g., telepathology services, second opinions, online      meetings) (optional)
  • Membrane, nucleus and TMA analysis modules      (optional)
  • Her-2 FISH, ALK FISH and translocation modules


Please contact us for further information

Technical support